Pyramids have been hit by another injury concern ahead of the Zamalek match after Mohamed El Shebi and Mahmoud Abdel Hafiz Zlaaka both picked up physical issues during recent preparations.
El Shebi left the friendly against Helwan after feeling pain in his knee, while Zlaaka missed the same game because of a heavy calf bruise, with both players now undergoing checks and treatment.
The latest setback comes after Mostafa Fathi's injury and adds further pressure on the coaching staff before a crucial match in the title race.
The medical team is expected to complete further assessments in the coming hours before a final decision is made on the pair's availability.